对自闭症谱系障碍儿童烧伤的回顾性分析
Lauren E Mazur1, Katelyn M Even2, Conrad Krawiec2
1Penn State College of Medicine, 500 University Drive, P.O. Box 850, Hershey, PA, 17033-0850, USA. lmazur@pennstatehealth.psu.edu.
Journal of autism and developmental disorders
|April 12, 2024
概括
患有自闭症谱系障碍 (ASD) 的儿童经历烧伤时面临更高的死亡风险和急性护理需求. 这项研究强调了美国儿童烧伤患者与ASD的死亡几率增加和重症监护需求.
科学领域:
- 儿童烧伤伤害的结果
- 神经发育障碍 研究 研究 神经发育障碍
- 临床信息学 临床信息学
背景情况:
- 患有神经发育障碍的儿童患烧伤伤害的风险增加.
- 在美国,患有自闭症谱系障碍 (ASD) 的儿科烧伤患者的临床结果,特别是死亡率,仍然在很大程度上未知.
- 了解这些结果对于有针对性的干预和改善患者护理至关重要.
研究的目的:
- 评估受试者的特征,烧伤类型,临床护理和ASD儿童的死亡率.
- 为了比较患有ASD和没有ASD的儿童在烧伤后的临床结果和重症监护管理.
- 为了测试这一假设,儿童烧伤患者与ASD与非ASD同行相比,具有相似的死亡率和急症护理需求.
主要方法:
- 使用TriNetX电子健康记录数据库进行的回顾性观察队列研究.
- 纳入标准:年龄在0-18岁的受试者,有烧伤诊断码.
- 对99,323名受试者的人口统计,诊断,药物,手术和死亡率数据的分析 (3,083名有ASD,96,240名没有ASD).
主要成果:
- 患有自闭症儿童的1年全因死亡率 (1.9倍) 的几率明显更高.
- 患有自闭症症的儿童烧伤患者需要重症监护服务 (1.88倍) 和机械通风 (2.69倍) 的几率增加.
- 这些发现与最初的假设相矛盾,表明ASD儿童的结果更差.
结论:
- 与没有ASD的儿童相比,患有自闭症谱系障碍 (ASD) 的美国儿童遭受烧伤的死亡率和急症护理需求的可能性更高.
- 这些发现强调了患有自闭症症的儿科烧伤患者的脆弱性,以及需要专门的护理考虑.
- 进一步的研究至关重要,以阐明导致这一群体死亡率增加和重症监护需求的具体因素.
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