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内皮功能障碍的影响增加了绝经后妇女对代谢反射激活的大动脉血液动力学反应

Mauricio A Martinez¹, Katherine N Dillon¹, Yejin Kang¹

¹Department of Kinesiology and Sport Management, Texas Tech University, 3204 Main St, Lubbock, TX, 79409, USA.

European journal of applied physiology

|April 12, 2024

概括

绝经后妇女的内皮功能障碍与运动恢复期间大动脉压力增加有关. 这一发现突显了这个人群中潜在的心血管风险因素.

科学领域:

心血管生理学心血管生理学
运动生理学运动生理学
血管生物学血管生物学

背景情况:

绝经后的女性表现出对异比握手运动和运动后肌肉缺血症的动脉动力反应加剧.
在这些生理压力因素期间,内皮功能,大动脉硬度和大动脉血动力学之间的相互作用仍然未被探索.

研究的目的:

为了研究内皮功能 (手臂动脉流介导扩张,口腔疾病) 和大动脉硬 (大动脉-大腿脉冲波速度,cfPWV) 与大动脉脉动性血液动力学之间的关系.
评估运动后肌肉缺血症 (PEMI) 和内皮功能期间大动脉血液动力学反应之间的关系.

主要方法:

大动脉血压,波反射和前后波压使用动脉计测量30名绝经后妇女.
参与者被分为低 (≤4.5%) 和正常 (≥5.5%) 的口炎组.
血液动力学反应被评估为在同位体握手运动和PEMI期间休息的变化.

主要成果:

与正常的口疾病组相比,患有低口疾病的女性对IHG的甲状腺静脉血压和脉压反应显著更高.
大动脉缩血压,脉冲压,增强压力和逆波压力对PEMI的反应在低口病组显著增加.
流媒扩张与大动脉血液动力学对PEMI的反应有负相关性,而cfPWV没有相关性.

结论:

内皮功能障碍与绝经后妇女在代谢反射激活期间大动脉脉动载荷增加有关.
这种增强的大动脉脉动载荷可能会在这个人口群体中增加心血管风险.

关键词:

衰老的衰老衰老的衰老动脉的硬性动脉的硬性自主神经系统的自主神经系统.脑内皮功能脑内皮功能运动可以提高血压.运动压力反射器反射.在高血压的高血压.

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