血管肉瘤在美国的发病率和表现特征,2001-2020年
Michael J Wagner1,2,3, Vinod Ravi4, Stephanie K Schaub5
1Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.
JAMA network open
|April 12, 2024
概括
2001年至2019年间,美国血管肉瘤的发病率翻了一番,女性的二次血管肉瘤显著增加,特别是在胸部和乳房. 早期检测对于这种侵袭性癌症至关重要.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 癌症研究 癌症研究
背景情况:
- 血管肉瘤是一种侵略性的血管新生瘤,可以是初级或二级,通常与放射治疗或淋巴有关.
- 关于血管瘤发病率和表现模式的全面数据对于理解和管理这种罕见的癌症至关重要.
研究的目的:
- 描述美国血管肉瘤的发病率,表现特征和时间趋势.
- 分析血管肉瘤诊断的人口和疾病范围模式.
主要方法:
- 一项回顾性横截面研究,利用美国癌症统计数据库 (USCS) 从2001年到2020年.
- 包括19289名被诊断为血管肉瘤的患者,从2023年6月到9月进行统计分析.
主要成果:
- 美国血管肉瘤发病率从2001年到2019年翻了一番,每年调整后的发病率增加了1.6%.
- 大多数病例是皮肤,皮下或乳腺血管瘤 (72.3%).
- 乳房,胸壁和上肢的二次血管瘤在女性中显著增加,内脏血管瘤的发病率也在增加.
结论:
- 血管肉瘤的发病率在美国有所增加,尤其是女性中影响胸部,乳房和上肢的次要类型.
- 这些发现强调需要提高对高风险人群的认识和改进早期检测策略,例如有乳腺癌史的女性.
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