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Updated: Jun 28, 2025

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糖溶解的HIF1α依赖性解抑制了瘤细胞的增殖

Andrés A Urrutia1, Claudia Mesa-Ciller1, Andrea Guajardo-Grence1

  • 1Research Unit, Hospital of Santa Cristina, Research Institute Princesa (IIS IP), Autonomous University of Madrid, 28009 Madrid, Spain.

Cell reports
|April 12, 2024
PubMed
概括

缺氧诱导因子-1α (HIF1α) 通过增加NADH/NAD+比率,减少乳酸分泌,令人惊地抑制糖解. 这种机制解释了HIF1α如何通过抑制细胞增殖作为瘤抑制剂,特别是在低酸盐环境中.

关键词:
CP: 癌症 癌症 癌症CP:新陈代谢过程中的新陈代谢.这就是HIF1α.它们是NADH和NADH.葡萄糖溶解是什么缺氧 缺氧是指缺氧的情况.线粒体中的线粒体.氧气 氧气 氧气 氧气细胞癌瘤是细胞癌.瘤是一个瘤.

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