改变加拿大专利药品清单价格上的参考国家的影响:政策分析
Wei Zhang1, Daphne P Guh2, Paul Grootendorst3
1Faculty of Pharmaceutical Sciences, University of British Columbia, 2405 Wesbrook Mall,Vancouver, BC V6T 1Z3, Canada; Centre for Advancing Health Outcomes, Providence Research, 570-1081 Burrard Street, Vancouver, BC V6Z 1Y6, Canada.
Health policy (Amsterdam, Netherlands)
|April 12, 2024
概括
加拿大加拿大加拿大加拿大加拿大加拿大
科学领域:
- 制药经济学 制药经济学
- 卫生政策分析 卫生政策分析
背景情况:
- 加拿大专利药品价格审查委员会 (PMPRB) 通过外部和内部参考定价 (IRP) 调节药品价格.
- PMPRB将其外部参考组从7个国家扩大到11个国家,以更好地与经合组织中位价格保持一致.
- 本研究分析了该PMPRB修正案对专利药物清单价格的潜在影响.
研究的目的:
- 评估PMPRB扩大参考定价对专利药物清单价格的影响.
- 评估与以前的MIP7.7相比,新的国际价格中位数 (MIP11) 的约束性.
- 在不同的定价情景下建模潜在支出变化.
主要方法:
- 利用IQVIA MIDAS®数据用于加拿大 (2013-2018) 推出的品牌产品.
- 在加拿大推出后的第三年计算出目录价格作为年平均价格.
- 使用 PMPRB7 和 PMPRB11 进行国际价格中位数比较,模拟了带有和没有 IRP 的情景.
主要成果:
- 在分析的400种产品中,有80.3%的产品价格处于扩大PMPRB11组.
- 对于大多数产品来说,MIP11并不具有约束力,在情景1中只导致支出减少0.7%.
- 如果产品推出顺序保持不变,废除IRP可能会使支出减少14.1%.
结论:
- 扩大PMPRB参考价格 (MIP11) 可能对大多数药品价格的影响有限.
- 价格监管的有效性取决于保持内部价格政策和MIP11之外的药品战略.
- 政策决策与IRP和处理非MIP的药物11对于支出控制至关重要.
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