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Updated: Jun 28, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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通过激活Nrf2通路,Protopine通过激活Nrf2通路来保护胆固醇细胞免受铁亡

Hongjie Chen1, Yiming Zhong2, Weilin Sang1

  • 1Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.

Biochemical and biophysical research communications
|April 12, 2024
PubMed
概括

通过减少炎症和铁亡,Protopine (PTP) 有效地保护关节软骨免受骨关节炎的影响. 这种异类醇激活Nrf2通路,为这种普遍的关节疾病提供了潜在的新疗法.

关键词:
冠状细胞 (chondrocytes) 是一种细胞.铁性化 (ferroptosis) 是一种Nrf2 没有任何问题.骨关节炎是一种骨关节炎.这种蛋白质叫做Protopine.

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