在严重抑郁症中全系统阿尤尔韦达管理协议的有效性-一个随机对照临床试验
Anjali Punia1, Sameeran Chate2, Basavaraj R Tubaki3
1Department of Kayachikitsa, IIMT Ayurveda Medical College and Hospital, Meerut, Uttar Pradesh, India.
Journal of Ayurveda and integrative medicine
|April 12, 2024
概括
全系统阿育吠陀管理协议 (WSAP) 有效治疗重度抑郁症 (MDD),显示出患者结果的显著改善和与传统治疗相比更好的副作用概况.
科学领域:
- 综合医学是一个整体的医学.
- 精神病学是一个精神病学.
- 艾尔韦达医学是一种医药.
背景情况:
- 重度抑郁症 (MDD) 是一种普遍存在的心理健康状况,对生活质量产生重大影响.
- 与MDD相关的高并发症率需要探索各种治疗方法.
- 全系统阿育吠陀管理协议 (WSAP) 提出了对MDD管理的潜在补充策略.
研究的目的:
- 评估全系统阿育吠陀管理协议 (WSAP) 在管理重大抑郁症 (MDD) 的有效性.
- 将WSAP的结果与MDD患者的标准药理治疗 (埃斯基塔洛普拉姆) 进行比较.
主要方法:
- 一项随机对照试验,涉及50名根据DSM V标准诊断的MDD患者 (20-70岁).
- 参与者被随机分为两组:接受埃斯基塔洛普拉姆的对照组和接受WSAP60天的Ayurveda组.
- 临床评估包括HDRS,HARS,BPRS,PSQI,WHOQOL-BREF,CGI和UKU副作用量表,每15天进行一次评估.
主要成果:
- 与对照组相比,Ayurveda组在HDRS (p=0.01),HARS (p=0.03),PSQI (p=0.03) 和WHOQOL-Bref (p<0.001) 中显著改善.
- 在WSAP组显示显著改善生活质量 (WHOQOL-Bref,p<0.001) 与一个大的效果大小.
- 艾尔维达组没有报告任何副作用,而对照组出现了轻微的副作用 (UKU尺度,p=0.02).
结论:
- 全系统阿育吠陀管理协议 (WSAP) 是一种有效的干预措施,用于管理严重抑郁症 (MDD).
- 与传统抗抑郁药物药物相比,WSAP提供了有利的副作用概况.
- 需要进一步的研究来验证和扩展这些发现.
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