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由NADPH氧化酶生成的活性氧物种参与17β-d-glucuronide诱导的雌激醇胆固醇酶

Gimena Salas1, Alen A Litta1, Anabela C Medeot1

  • 1Instituto de Fisiología Experimental (IFISE), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Ciencias Fisiológicas, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina.

Biochimie
|April 12, 2024
PubMed
概括

Estradiol 17β-D-glucuronide (E17G) 通过增加氧化应激和内化 Mrp2 载体,导致胆固醇形成. 抗氧化剂和NADPH氧化酶抑制阻止了这种情况,突出了怀孕胆固醇形成的一个新机制.

关键词:
在ERK1/2中.Estradiol 17β-D-glucuronide 是一种 17β-D-glucuronide 的类型,它是一种 17β-D-glucuronide 的类型,它是一种 17β-D-glucuronide 的类型.在 Mrp2 中,您可以使用 Mrp2 .在NADPH氧化酶.有反应性氧物种的反应性氧物种.p38MAPKKK 在线阅读

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