在接受重血管化治疗的患者中,长期患者报告的结果与间歇性音治疗的药物治疗相比
Teryn A Holeman1, Cassidy Chester2, Julie B Hales2
1Division of Vascular Surgery, University of Utah, School of Medicine, Salt Lake City, UT; Department of Population Health Science, University of Utah, School of Medicine, Salt Lake City, UT.
Journal of vascular surgery
|April 12, 2024
概括
对于间歇性声 (IC),手术复血管化和非手术管理产生类似的长期身体功能. 两组患者对社交活动的满意度都有所提高,非手术治疗显示出轻微的优势.
科学领域:
- 血管外科 血管外科
- 患者报告的结果
- 相对的有效性比较
背景情况:
- 血管外科协会的指导方针建议在间歇性关节障碍 (IC) 中进行再血管化,以改善功能和生活质量.
- 目前还没有证据表明手术干预是否能为IC患者提供优越的功能益处,而不是仅仅为IC患者提供最佳的医疗管理.
- 这项研究比较了患者报告的IC的手术和非手术治疗之间的结果.
研究的目的:
- 检查IC治疗方式 (再血管化与非手术治疗) 和患者报告的结果之间的关系.
- 评估身体功能 (PROMIS-PF) 和对社会角色和活动 (PROMIS-SA) 的满意度的变化.
- 为了确定再血管化是否与IC的非手术治疗相比,提供了显著的功能益处.
主要方法:
- 鉴定了IC患者,并将其分为重血管化或非手术管理组.
- 使用线性混合效应模型分析了PROMIS-PF,PROMIS-SA和脚-手臂指数 (ABI) 随着时间的推移的趋势.
- 模型根据临床共变量进行调整,包括年龄,性别,糖尿病,并发症,虚弱,吸烟和基线ABI.
主要成果:
- 随着时间的推移,在复血管化和非手术管理组之间没有观察到PROMIS-PF的显著差异.
- 所有IC患者在随访期间表现出PROMIS-SA显著改善.
- 非手术治疗的患者在PROMIS-SA中表现出较大的改善,而不是那些接受了再血管化治疗的患者.
结论:
- 患者报告的功能状态和对活动的满意度在IC患者的7年内是可比的,无论治疗方式如何.
- 结果表明,保守的非手术治疗可能是IC患者的合适的长期方法.
- 这项研究支持考虑非手术治疗作为改善IC患者生活质量的首要策略.
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