定义确定的高血压的成年人抗高血压药物坚持有意义的变化:对临床实践的影响
Erin Peacock1, Paul Muntner2, Leslie S Craig3
1Department of Medicine, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA; Center for Health Outcomes, Implementation, and Community-Engaged Science, Tulane University School of Medicine, 1430 Tulane Avenue, New Orleans, LA 70112, USA.
The Medical clinics of North America
|April 12, 2024
概括
检测抗高血压药物的坚持有意义的变化对于管理高血压至关重要. 克鲁塞尔-伍德尺度上的2点偏移意味着影响血压控制的坚持变化.
科学领域:
- 心脏病学 心脏病学
- 临床药房 临床药房
- 公共卫生 公共卫生
背景情况:
- 失控的高血压和不良的药物坚持是持续的临床问题.
- 准确测量粘附变化对于有效的高血压管理至关重要.
- 目前的方法可能无法充分捕捉临床上显著的粘附性转变.
研究的目的:
- 通过使用Krousel-Wood药物坚持度表来确定抗高血压药物坚持度有意义变化的门.
- 为了研究粘附和血压控制的有意义变化之间的关联.
主要方法:
- 利用来自正在进行的临床试验的参与者的数据.
- 应用了Krousel-Wood 4项药物坚持度表来评估坚持.
- 分析了6个月后粘附变化和血压测量之间的关系.
主要成果:
- 克鲁塞尔-伍德等级分数下降≥2分被确定为坚持有意义的下降.
- 5.9%的参与者表现出坚持的显著下降.
- 降低粘附性与血压升高和不受控制的高血压的患病率增加有关.
结论:
- 克鲁塞尔-伍德尺度上≥2点的变化可靠地表明抗高血压药物坚持的有意义的转变.
- 监测有意义的坚持变化对于改善血压控制至关重要.
- 针对药物坚持行为的干预措施可以提高高血压管理和患者的结果.
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