饮食中摄入的B族维生素与玻璃眼的相关性
Jingjing Hou1,2, Yu Wen1,2, Sijia Gao1,2
1Department of Ophthalmology, The Second Affiliated Hospital of Anhui Medical University, 678 Furong Road, Hefei, Anhui, China.
Scientific reports
|April 12, 2024
概括
摄入更多的某些B族维生素,如B1,B2,B6和B12,可能会降低青光眼的风险. 这种饮食联系在自我报告和临床诊断的玻璃眼病例中都被观察到.
科学领域:
- 营养科学 营养科学
- 眼科医生 眼科 眼科
- 流行病学 流行病学
背景情况:
- 玻璃眼是全球不可逆转的失明的主要原因.
- 包括B族维生素在内的食因素越来越多地被认为对眼睛健康的潜在作用.
- 了解B族维生素摄入量与玻璃眼之间的关系,可以为预防策略提供信息.
研究的目的:
- 调查各种B族维生素的饮食摄入量与玻璃眼的患病率之间的关联.
- 探索这种关联中的潜在的性别特异性差异.
- 为了确定可能对玻璃眼瘤有保护作用的特定B族维生素.
主要方法:
- 横截面研究涉及5025名参与者进行自我报告的青光眼和3264名ISGEO标准.
- 使用了关于青光眼状况和饮食摄入量评估的问卷.
- 采用了统计分析,包括赔率比率,置信区间,趋势测试和限制的立方轴线分析,用于非线性.
主要成果:
- 增加维生素B1的摄入量与自我报告的青光瘤的几率较低有关 (OR 0.63).
- 在男性中,较高的维生素B1 (OR 0.44) 和维生素B2 (OR 0.39) 摄入量与降低眼风险相关.
- 尼亚摄入量与玻璃眼 (OR 0.94) 有负面关联,而维生素B6摄入量与男性的几率降低有关 (OR 0.21).
- 在女性的维生素B2和B9摄入量与ISGEO诊断的玻璃眼之间发现了非线性关联.
结论:
- 通过饮食摄入特定的B族维生素 (B1,B2,B6,B12,尼雅) 可能在降低青光眼风险方面发挥作用.
- 维生素B和玻璃眼之间的关联似乎是某些维生素的性别特异性.
- 需要进一步的研究来证实这些发现并阐明涉及的机制.
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