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Updated: Jun 6, 2026

Induction of Murine Intestinal Inflammation by Adoptive Transfer of Effector CD4+CD45RBhigh T Cells into Immunodeficient Mice
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布林普-1和c-Maf调节免疫基因网络,以防止病原体诱导的大肠炎的不同途径

Marisol Alvarez-Martinez1, Luke S Cox1, Claire F Pearson2

  • 1Immunoregulation and Infection Laboratory, The Francis Crick Institute, London, UK.

Nature immunology
|April 12, 2024
PubMed
概括

转录因子Blimp-1和c-Maf控制细胞因子IL-10以防止肠道炎症. 它们的缺失导致严重的结肠炎,并揭示了人类炎症性肠病背后的机制.

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