在腹腔和切口修复术后阿片类药物使用的预测因素
Do Hyun Yun1, Margaret A Plymale2, Douglas R Oyler3
1College of Medicine, University of Kentucky, Lexington, KY, USA.
Surgical endoscopy
|April 12, 2024
概括
在手术前使用阿片类药物显著增加了腹腔和切口修复 (VIHR) 患者的术后阿片类药物需求. 像阿片类药物耐受性和伤口感染等因素预测了手术后更高的阿片类药物利用率.
科学领域:
- 手术成果研究的研究结果.
- 疼痛管理 疼痛管理
- 药物监督 药物监督 药物监督
背景情况:
- 在腹腔和切口修复 (VIHR) 患者中,很大一部分患者接受了手术前的阿片类药物处方.
- 了解影响术后阿片类药物使用的因素对于优化疼痛管理和减少阿片类药物依赖至关重要.
研究的目的:
- 确定与VIHR患者术后阿片类药物处方填充量增加相关的风险因素.
- 为了比较患有和没有手术前阿片类药物处方的患者的阿片类药物使用情况.
主要方法:
- 对2013-2017年VIHR案件的回顾性审查.
- 国家处方药监测计划数据与患者记录的整合.
- 主要终点:离院后长达45天的累积阿片类药物剂量,以吗啡毫克相当量 (MME) 计量.
主要成果:
- 这项研究包括205名VIHR患者 (平均年龄为53.5岁,50.7%为女性).
- 超过35%的患者在手术前使用过阿片类药物.
- 手术前的阿片类药物耐受性,表面伤口感染,目前的吸烟以及在入院前45天内使用的任何阿片类药物都是术后阿片类药物使用增加的独立预测因素 (p < 0.001).
结论:
- 在入院前45天内进行手术前的阿片类药物使用与VIHR患者的术后阿片类药物处方填充量增加密切相关.
- 确定了几种独立的风险因素,可以预测手术后阿片类药物使用率更高.
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