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肥胖儿童和青少年的自主功能:系统审查和元分析
Georgios E Papadopoulos1, Foteini Balomenou2, Xenofon M Sakellariou1
1Department of Cardiology, Faculty of Medicine, University of Ioannina, 45110 Ioannina, Greece.
Journal of clinical medicine
|April 13, 2024
概括
肥胖儿童和青少年由于阴道活动减少而表现出自主功能障碍. 这一系统性审查强调了对儿童肥胖症中的同情性活动的进一步研究的需要.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 自主神经系统研究 自主神经系统研究
- 肥胖和新陈代谢 肥胖和新陈代谢
背景情况:
- 肥胖与自主功能障碍有关,但儿科数据不一致.
- 了解儿童肥胖症的自主功能对于健康结果至关重要.
研究的目的:
- 系统地审查和分析关于肥胖与正常体重儿童和青少年自主功能障碍的研究.
- 量化心率变化的同情和阴道指数的差异.
主要方法:
- 12项研究的系统综述和元分析,包括1102名参与者 (年龄为5-18岁).
- 肥胖 (BMI >95百分位) 和正常体重 (BMI <85百分位) 群体的比较.
- 利用随机效应模型计算心率变化指数的标准化平均差异 (SMD).
主要成果:
- 肥胖的受试者表现出自主功能障碍,SMD指的是鼻腔间隔的标准偏差 (-0.5340) 和LF/HF比率 (0.5735).
- 在肥胖儿童中观察到下阴道活动,其证据是HF (0.5876),RMSSD (-0.6333) 和pNN50 (-0.5867) 中的SMD.
- 在同情活动中没有发现显著差异,尽管研究异质性限制了这一结论.
结论:
- 自主功能障碍,以减少阴道活动为特征,存在于肥胖儿童和青少年中.
- 建议在多样化的儿科队伍中进行进一步的研究,重点关注交感神经系统活动.
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