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在COVID-19急性呼吸系统综合征治疗的非侵入性呼吸支持的振荡计纵向数据
Chiara Torregiani1, Elisa Baratella2, Antonio Segalotti2
1Pulmonology Unit, Department of Medical Surgical and Health Sciences, University of Trieste, Hospital of Cattinara, 34149 Trieste, Italy.
Journal of clinical medicine
|April 13, 2024
概括
使用振荡计的非侵入性肺力学测量在COVID-19 ARDS患者在氧气支持下是可行的. 随着时间的推移,肺部机制得到了改善,但没有预测不良结果,这表明复杂的COVID-19 ARDS病理生理学.
科学领域:
- 肺部医学 肺部医学
- 关键的护理关键的护理
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 在COVID-19患者中,急性呼吸窘迫综合征 (ARDS) 呈现出复杂的呼吸机制.
- 非侵入性氧气支持 (NI-OS) 是这些患者的常见治疗方式.
- 了解肺部机制对于管理COVID-19 ARDS至关重要.
研究的目的:
- 在接受NI-OS.OS的COVID-19ARDS患者中评估肺机械.
- 为了将肺机械与临床和成像发现相关联.
- 确定肺机械学是否可以预测临床结果.
主要方法:
- 在1日,4日和7日进行振荡计 (R5,X5,ΔX5,R5-R19) 的32名COVID-19ARDS患者的回顾性分析.
- 振荡计与计算机断层扫描肺血管造影 (CTPA) 数据的相关性.
- 定义不良结果为输管或死亡.
主要成果:
- 在NI-OS的重症COVID-19 ARDS患者中,振荡计是可行的.
- 肺机械 (R5,R5-R19,ΔX) 在住院期间普遍有所改善,而X5增加.
- 在CTPA上,X5的z-score与肺部缩区域相关,但不是空气不足的区域.
- 最初的振荡计参数没有预测研究队列中的不良结果.
结论:
- 振荡计是一种可行的工具,用于监测NI-OS上的COVID-19 ARDS患者的肺机械.
- X5 z分数可能反映了COVID-19肺炎中的肺部崩.
- 这些发现表明,COVID-19 ARDS中存在复杂的生理病理学,尽管反应力正常,但可能存在气体交换障碍.
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