相关实验视频

Updated: Jun 28, 2025

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography

Published on: March 26, 2020

在心力衰竭中视网膜血管变化与保存的射出分数使用光学一致性断层扫描血管学

Jerremy Weerts¹, Anne G Raafs¹, Birgit Sandhoefner²

¹Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre+ (MUMC+), P.O. Box 616, 6200 MD Maastricht, The Netherlands.

Journal of clinical medicine

|April 13, 2024

概括

患有心力衰竭和保留射出分数 (HFpEF) 的患者表现出视网膜血管变化,包括血管密度降低和视网膜层厚度降低. 这些变化与扩张功能障碍相关,这表明OCT-A是监测HFpEF进展的工具.

科学领域:

眼科医生眼科眼科
心脏病学心脏病学
医疗成像医学成像

背景情况:

系统性微血管功能障碍与心脏衰竭有关,心脏衰竭具有保存的射出分数 (HFpEF).
在HFpEF中视网膜微血管和结构变化仍然在很大程度上没有特征.

研究的目的:

通过光学相干断层扫描血管学 (OCT-A) 来研究HFpEF患者和对照组之间视网膜微血管和结构参数的差异.
在HFpEF中评估视网膜参数与腹功能障碍的临床/心声学标志物之间的关联.

主要方法:

一项前性研究,比较了22名HFpEF患者和24名对照组.
使用OCT-A进行视网膜成像,以评估斑点血管密度和视网膜层厚度.
对HFpEF患者进行心声扫描,以评估腹功能.

主要成果:

与对照组相比,HFpEF患者表现出明显较低的斑点血管密度和斑点质细胞内状层厚度.
在HFpEF患者中观察到对视网膜总体积较低的趋势.
在HFpEF中减少的视网膜总体积与舒张功能障碍的标志物有关,独立于混因素.

结论:

HFpEF与明显的视网膜血管和结构变化有关.
通过OCT-A检测到的视网膜变化与HFpEF中扩张功能障碍的严重程度相关.
OCT-A显示了在HFpEF中监测系统微血管变化和心脏扩张功能的潜力.

关键词:

在 LV 腹筋功能障碍.其他国家,地区和地区-A.心力衰竭与保存的喷射分数的心脏衰竭图像成像生物标志物生物标志物微血管密度微血管密度视网膜的改变视网膜的改变

更多相关视频

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

相关概念视频

Pathophysiology of Heart Failure

Pathophysiology of Heart Failure

Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...

Imaging Studies for Cardiovascular System I:Echocardiography

Imaging Studies for Cardiovascular System I:Echocardiography

Cardiac imaging studies encompass a wide range of noninvasive and minimally invasive techniques designed to visualize the heart's structure and function in detail. One such technique is echocardiography, which uses high-frequency ultrasound waves to produce detailed images of the heart, known as echocardiograms.
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...