身体功能结果在癌症的临床相关性 Cachexia
Lucas Caeiro1,2, Sofia Jaramillo Quiroz1,2, Jenna S Hegarty1
1Geriatric Research, Education and Clinical Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98108, USA.
Cancers
|April 13, 2024
概括
确定癌症缓解症中的功能障碍对于治疗开发至关重要. 这份综述表明,手握强度不足3-6公斤可能表明癌症缓冲症患者的临床相关性.
科学领域:
- 在瘤学瘤学.
- 临床医学 临床医学
- 康复科学 康复科学 康复科学
背景情况:
- 管理癌症和治疗对患者功能和生活质量的副作用至关重要.
- 癌症缓冲症显著降低功能能力,但缺乏明显的障碍标准.
- 这种差距阻碍了癌症缓解症的有效治疗方法的开发.
研究的目的:
- 审查临床上有意义的功能障碍标准的证据,在癌症患者有或没有缓冲症.
- 评估癌症缓解症干预研究中的随时间变化的身体功能变化标准.
主要方法:
- 对横截面和干预研究的文献综述.
- 专注于功能评估,特别是手握强度 (HGS).
主要成果:
- 手握强度是最常见的功能评估.
- 在HGS中3-6公斤的赤字可能对癌症缓解症具有临床意义.
- 专注于骨肌的多式疗法可以改善体重减轻的卡塞克斯患者的HGS.
结论:
- 需要临床相关的标准来确定癌症缓解症中的功能障碍.
- 进一步的研究应该建立队列特定的标准,并探索患者报告的结果.
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