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结肠直肠癌肺转移切除术:什么时候,为什么和如何

Francesco Petrella¹, Federica Danuzzo¹, Maria Chiara Sibilia¹

¹Division of Thoracic Surgery, Fondazione IRCCS San Gerardo dei Tintori, Via GB Pergolesi 33, 20900 Monza, Italy.

|April 13, 2024

概括

大肠直肠癌 (CRC) 肺转移是一个重大的临床挑战. 手术切除是符合条件的患者最有效的治疗方法,改善了结果.

科学领域:

在瘤学瘤学.
胸部外科手术胸部外科手术
胃肠病学胃肠病学

背景情况:

结肠直肠癌 (CRC) 是全球癌症相关死亡的主要原因.
大约20%的CRC患者在诊断时存在转移性疾病.
来自CRC的肺转移对胸部外科医生和瘤学家来说是一个重大挑战.

研究的目的:

审查结直肠癌肺转移的临床方法.
为了确定符合肺转移局部治疗条件的患者的预后因素.
讨论手术切除在控制CRC肺转移中的作用.

主要方法:

对结直肠癌肺转移的研究进行文献综述.
分析治疗策略,包括手术切除,SBRT和切除.
确定影响肺转移切除术后结果的预后因素.

主要成果:

大约9-12%的CRC肺转移患者是局部激进治疗的候选人.
手术切除被认为是最有效的治疗选择.
主要瘤切除,瘤生物学,无疾病间隔和无进展生存是关键的预后因素.

结论:

确定的CRC肺转移患者队列可以从肺转移切除术中显著受益.
需要进一步的研究,以确定最佳局部治疗策略的最终证据.
多学科管理对于优化CRC肺转移的结果至关重要.

关键词:

结肠直肠癌是什么意思没有疾病的时间间隔.总体存活率总体存活率肺转移切除术是指肺转移切除术.

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