机械坚固和导电性水凝基于凝和Z-Gln-Gly产生的微生物转质氨酶
Zhiwei Chen1, Ruxin Zhang1, Shouwei Zhao1
1State Key Laboratory of Biobased Material and Green Papermaking, Faculty of Light Industry, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250353, China.
Polymers
|April 13, 2024
概括
本研究介绍了一种使用酶交叉连接来制造具有增强机械强度和导电性的导电凝 (Gel-TG-ZQG) 的新方法. 这些新的水凝显示出可穿戴生物传感器和健康监测的前景.
科学领域:
- 材料科学 材料科学 材料科学
- 生物材料工程 生物材料工程
- 聚合物化学 聚合物化学
背景情况:
- 凝水凝对于生物医学应用具有吸引力,但往往缺乏足够的机械强度和导电性.
- 制造具有可调节性质的导电凝水凝仍然是一个重大挑战.
研究的目的:
- 开发一种创新的方法,以制备具有改善机械性能和导电性的基于凝的导电水凝.
- 调查Z-Gln-Gly集成和碳基团在提高水凝性能方面的作用.
- 为了证明这些水凝作为可穿戴设备的敏感和稳定的生物传感器的潜力.
主要方法:
- 凝与Z-Gln-Gly的酶交联形成凝-TG-ZQG水凝.
- 水凝机械性质的表征 (储存模量,压力强度,抗拉强度,破裂时的延长).
- 评估水凝导电性和传感器性能,包括响应/恢复时间和灵敏度.
- 评估传感器检测各种人类活动和细胞毒性的能力.
主要成果:
- 优化的Gel-TG-ZQG (0.25) 水凝表现出优异的机械性能 (例如,7.8MPa储存模块,破裂时218.30%的延长).
- 基于水凝的应变传感器表现出高灵敏度 (0.138 kPa-1) 和快速响应/恢复时间 (260.37 ms/130.02 ms).
- 传感器成功检测出了一系列具有高稳定性和可重复性的人类活动,并发现水凝是非细胞毒性的.
结论:
- 开发的Gel-TG-ZQG水凝为先进的生物传感应用提供了一个有前途的平台.
- 可调节的机械和导电性质使它们适用于可穿戴设备和健康监测系统.
- 这种方法提供了一个可行的策略,用于制造高性能导电性水凝从凝.
相关概念视频
01:30Environmental Applications of Microorganisms
Microorganisms play a pivotal role in maintaining ecosystem balance by recycling essential elements such as carbon, nitrogen, and phosphorus, as well as supporting processes like bioremediation, wastewater treatment, and biofuel production.Microbes in Elemental CyclesIn the carbon cycle, microorganisms decompose organic matter, releasing carbon dioxide via aerobic respiration. This carbon dioxide is subsequently used by photosynthetic organisms to synthesize organic compounds, closing the...
01:23Microbial Fermentation
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
01:26Microbes and Methanogenesis
Methanogenesis is a critical microbial process in anaerobic ecosystems responsible for the biological production of methane, a potent greenhouse gas and valuable biofuel. This metabolic pathway is primarily facilitated by methanogenic archaea, which thrive in anoxic environments such as wetlands, sediments, and animal gastrointestinal tracts. The absence of oxygen in these habitats prevents aerobic respiration, thereby favoring alternative biochemical pathways for organic matter degradation.In...
01:23Microbial Fuel Cells
Microbial fuel cells (MFCs) are bioelectrochemical devices that generate electricity by exploiting the metabolic processes of electrogenic bacteria. These systems provide a renewable energy source and serve as an innovative method for treating organic waste, such as wastewater.A typical MFC consists of two chambers: an anoxic (oxygen-free) compartment that houses the bacteria and an oxic (oxygen-rich) compartment that contains oxygen as the terminal electron acceptor. Many MFCs use proton...
01:25Production of Organic Acids
Lactic acid, an important organic acid extensively applied in food, pharmaceutical, and biodegradable polymer industries, is primarily produced via microbial fermentation. This method is favored over chemical synthesis due to its environmental sustainability and capacity for enantiomerically pure product formation. Among various microbial processes, the fermentation of starch-based substrates stands out due to the abundance and renewability of raw materials like corn and potatoes.Hydrolysis of...
01:28Microbial Bioremediation of Plastics
Polyethylene terephthalate (PET) is a synthetic polymer widely utilized in the packaging industry, particularly for bottles and containers. Due to its chemical stability and durability, PET accumulates in the environment, contributing significantly to plastic pollution. It comprises repeating units of terephthalic acid and ethylene glycol, resulting in a semi-crystalline structure that is resistant to natural degradation processes.A notable breakthrough in plastic biodegradation came with the...