黄化合物化学结构与其抗氧化能力之间的关系 防止多环芳香碳化合物在加热肉类模型系统中的形成
Thi Thu Huong Huynh1, Wanwisa Wongmaneepratip2, Kanithaporn Vangnai1
1Department of Food Science and Technology, Faculty of Agro-Industry, Kasetsart University, Bangkok 10900, Thailand.
Foods (Basel, Switzerland)
|April 13, 2024
概括
饮食中的黄类化合物可以抑制加热肉中的多环芳 (PAHs) 形成. 瑞显示出最高的抑制,与其抗氧化剂和自由基清除能力相关,证明了减少PAH的结构-活性关系.
科学领域:
- 食品化学 食品化学
- 分析化学 分析化学
- 营养科学 营养科学
背景情况:
- 多环芳 (PAH) 是高温食品加工过程中形成的有害化合物.
- 黄酸是植物衍生化合物,具有已知的抗氧化特性.
- 了解黄胺结构如何影响PAH抑制对于食品安全至关重要.
研究的目的:
- 在加热肉模型中,研究六种黄素的化学结构与它们在抑制PAH形成中的有效性之间的关系.
- 为了将黄类抗氧化剂活性与它们降低PAH水平的能力相关联.
主要方法:
- 在一个加热的肉类模型中,六种黄素被测试了它们对PAH8形成的抑制作用.
- 用QuEChERS与气体染色体质谱法 (GC-MS) 相结合来量化PAH水平.
- 通过DPPH,ABTS和FRAP测定来评估抗氧化活性.
主要成果:
- 黄类药物的抑制有所不同:米瑞 (72.1%) > 莫林 (55.7%) > 奎尔塞丁 (57.3%) > 凯姆菲罗尔 (49.9%) > 鲁丁 (32.7%) > 塔克西福林 (30.2%).
- 在黄类抗氧化剂活性和PAH降低之间观察到显著的负相关性.
- 米瑞的结构,具有多个基团和特定的环结合,与高抗氧化和PAH抑制活性相关.
- 在C-3位置的替代物 (rutin,taxifolin) 降低了抑制作用.
结论:
- 黄化合物的化学结构决定了它们在抑制PAH形成方面的有效性.
- 抗氧化能力,特别是自由基清除能力,是弗拉诺酸抑制PAH的关键因素.
- 基于其结构,饮食中摄入特定的黄类素可以作为减轻受加热食品引起的PAH暴露的策略.
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