人类诺罗病毒替代品在果果汁中高度稳定,在体外模拟消化下高度稳定
1Center for Food Safety, Department of Food Science and Technology, University of Georgia, Griffin, GA 30223, USA.
Foods (Basel, Switzerland)
|April 13, 2024
概括
图兰病毒 (TV),一种诺罗病毒替代品,在果果汁中和模拟消化过程中保持稳定. 这凸显了防止果污染的重要性,以减少食源性疾病的爆发.
科学领域:
- 食品安全 食品安全
- 病毒学 病毒学
- 胃肠病学 胃肠病学
背景情况:
- 人类诺罗病毒是导致食物传播疾病的首要原因,经常与果消费有关.
- 了解食物矩阵和胃肠道中的病毒持久性对于风险评估至关重要.
研究的目的:
- 为了评估图兰病毒 (TV) 的稳定性和传染性,这是人类诺罗病毒的替代品,在蓝和草果汁中.
- 通过使用INFOGEST模型模拟胃肠道消化来评估电视持续性.
主要方法:
- 电视被注入蓝和草果汁中,并在4°C和37°C化.
- 果汁经历了顺序模拟的消化 (口腔,胃,肠道) 遵循INFOGEST协议.
- 使用50%组织培养感染剂量 (TCID50) 试验量化了传染性TV.
主要成果:
- 在4°C下120分钟的时间内,电视传染性在两种滑水中都稳定.
- 在37°C的温度下,TV在60分钟后显示蓝牛奶的含量略有减少 (~0.5 log TCID50/mL).
- 在模拟消化过程中,TV在两种果汁类型的果汁中基本保持稳定,在蓝果汁中观察到的最小减少.
结论:
- 传染性图兰病毒在果果汁中以及在模拟胃肠道过境期间表现出显著的稳定性.
- 在消费前防止果受到诺罗病毒污染对于减轻食源性疫情至关重要.
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