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Meng Meng^1,2,3, Ziyi She^1,2,3, Yinyin Feng^1,2,3

¹State Key Laboratory of Food Nutrition and Safety, College of Food Science and Engineering, Tianjin University of Science and Technology, No. 29, 13th Avenue, Tianjin Economy Technological Development Area, Tianjin 300457, China.

Foods (Basel, Switzerland)

|April 13, 2024

概括

研究人员开发了具有显著血管酶转化酶 (ACE) 抑制和抗氧化活性的核桃粉. 这些,特别是低于3kDa的,尽管在消化后活性降低,但作为功能性食品成分具有前景.

科学领域:

食品科学食品科学食品科学
生物化学生物化学
营养保健品营养保健品

背景情况:

核桃粉是石油提取的副产品,富含蛋白质.
价值化农业副产品如核桃粉对于可持续性至关重要.
ангиотензин转化酶 (ACE) 抑制剂对于治疗高血压很重要.

研究的目的:

为了从核桃粉中制备和表征ACE抑制性.
为了最大限度地优化提取过程以获得最大限度的ACE抑制活性.
为了评估的抗氧化特性和胃肠道稳定性.

主要方法:

使用性溶液和酸沉提取蛋白质.
通过单因素实验和响应表面方法论进行过程优化.
使用超过和体外抗氧化剂试验进行酸分离.
模拟胃肠道消化以评估的稳定性.

主要成果:

在最佳条件下,核桃粉水解剂 (WMH) 具有63.93%的ACE抑制.
<3 kDa分数表现出最高的ACE抑制活性.
观察到显著的体外抗氧化活性 (例如,DPPH IC50:0.25 mg/mL).
在模拟消化后,核桃保留了>90%的ACE抑制活性.

结论:

低分子量核桃具有强大的ACE抑制和抗氧化特性.
核桃粉是生产功能性的可行来源.
这些具有作为功能性食品和营养药品天然成分的潜力.

关键词:

的ACE抑制率.抗氧化抗氧化剂酶性水解是一种酶性水解.稳定的稳定性稳定的稳定性胡果粉是什么意思胡果粉是什么意思

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