用常见的草来开发生物活性材料的应用
Alina Ioana Lupuliasa1, Anda-Maria Baroi2,3, Sorin Marius Avramescu4,5
1Department of Physical and Colloidal Chemistry, Faculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia Str., 020956 Bucharest, Romania.
Plants (Basel, Switzerland)
|April 13, 2024
概括
伊索普和鱼提取物被用来通过绿色合成制造银纳米粒子. 微波辅助提取产生了具有显著生物活性的强有力的抗氧化纳米颗粒,显示了纳米技术应用的前景.
科学领域:
- 植物化学 植物化学
- 纳米技术纳米技术
- 生物技术是生物技术.
背景情况:
- 芝麻 (Hyssopus officinalis L.) 和菜 (Origanum vulgare L.) 具有传统的抗菌性能.
- 这些植物是纳米技术的可行候选者,特别是金属纳米颗粒的绿色合成.
研究的目的:
- 为了评估芝麻和鱼的银纳米粒子植物合成.
- 评估植物提取物和合成纳米粒子的生物活性 (抗氧化剂,细胞活力,炎症,细胞毒性).
主要方法:
- 采用了两种提取方法:经典温度提取和微波辅助提取.
- 使用高性能液体染色学 (HPLC) 分析了植物化学成分.
- 纳米粒子使用X射线衍射 (XRD) 和传输电子显微镜 (TEM) 进行了表征.
主要成果:
- 与经典提取相比,微波辅助提取产生了较高的总化合物 (TPC).
- Oregano 提取物始终显示TPC比石提取物更高.
- 最小的纳米粒子 (2.94纳米晶体体尺寸通过XRD,10纳米平均直径通过TEM) 用鱼微波提取物产生.
- 菜微波取物中的纳米粒子表现出显著的抗氧化特性 (>60%的DPPH抑制).
- 在低度下,细胞活力不受影响,与氧化水平相关.
- 草提取物纳米颗粒对细胞膜完整性没有影响,与增加LDH的其他样本不同.
结论:
- 微波辅助提取是优越的,以获得丰富的植物化学物质提取物从伊索普和菜纳米粒子合成.
- Oregano 微波取物对于生产小的,高度抗氧化银纳米颗粒特别有效.
- 合成的纳米颗粒显示出有前途的生物活性,为治疗和纳米医学应用提供了进一步的研究.
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