对患有特纳综合征的女性进行全面的口腔诊断和管理
Victoria Tallón-Walton1, Meritxell Sánchez-Molins2, Wenwen Hu1
1Human Anatomy and Embryology Unit, Experimental Pathology and Therapeutics Department, University of Barcelona, 08907 Barcelona, Spain.
Diagnostics (Basel, Switzerland)
|April 13, 2024
概括
在患有特纳综合征 (TS) 的女性中,早期发现特定的口腔和面异常至关重要. 在9-10岁的儿童中识别这些症状可以改善临床管理和长期健康结果.
科学领域:
- 遗传学 是一个遗传学.
- 儿科 儿科 儿科
- 牙科 牙科是指牙科的专业.
背景情况:
- 特纳综合征 (TS) 是一种罕见的遗传疾病,由于部分或完全缺失X染色体而影响女性.
- 在TS遗传和表型的高变异性复杂的诊断和临床管理,经常推迟到青春期.
- 目前缺乏对TS口腔,牙和面异常的全面了解.
研究的目的:
- 对女性TS进行口腔健康和面特征的详细分析.
- 为了确定与TS相关的特定牙和面异常.
- 确定早期检测对于改进TS管理的重要性.
主要方法:
- 分析15名TS女性及其一级亲属队列中的口腔健康和头骨面部特征.
- 利用多功能系统来识别和记录症状和症状.
- TS受试者的年龄范围:3至48岁.
主要成果:
- 在TS受试者中发现的多种迹象和症状的聚合,包括牙异常 (超数,生殖,微牙,牙缺陷,喷发变化,拥挤,旋转,转移).
- 在TS患者中观察到缺陷 (II/1和II/2类) 和II类面部形状.
- 与TS受试者相比,亲属表现出较少的TS相关表现.
结论:
- 早期检测特定的口腔和头骨面部症状对于及时转诊和TS的最佳临床管理至关重要.
- 在9-10岁左右出现的先天性牙异常是早期TS识别的关键指标.
- 使用已建立的分类学来描述表型和多学科团队护理对于TS的整体管理至关重要.
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