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中型环扩展策略:增强小分子图书馆开发

Hwiyeong Lee1, Jonghoon Kim2, Minseob Koh1

  • 1Department of Chemistry and Chemistry Institute for Functional Materials, Pusan National University, Busan 46241, Republic of Korea.

Molecules (Basel, Switzerland)
|April 13, 2024
PubMed
概括

合成中等大小的环对于药物发现至关重要,使得难以向的蛋白质成为目标. 本综述探讨了创新的合成策略,以克服挑战,并扩大新药的化学多样性.

关键词:
发现生物活性化合物发现.面向多样性的综合.一个中型的环合成环.自然产品模仿自然产品的模仿.环膨胀反应是指环膨胀反应.

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