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表面残余应力对骨质母细胞反应和细菌殖民化的影响

Rita Pereira¹, Paulo Maia², Jose Vicente Rios-Santos¹

¹Facultad de Odontología, Universidad de Sevilla, Calle Avicena s/n, 41009 Sevilla, Spain.

Materials (Basel, Switzerland)

|April 13, 2024

概括

牙植入物中的残留应力增强骨细胞粘附和性酸酶 (ALP) 水平,改善骨质整合. 粗性主要影响骨质母细胞的反应,而细菌更喜欢粗的表面.

科学领域:

生物材料科学生物材料科学
整形外科的研究研究.
牙科植入物学牙科植入物学

背景情况:

石爆破是牙植入物的标准,为骨生长创造了粗.
来自砂喷射的压缩残余应力的对植入物生物学的影响还未得到充分研究.

研究的目的:

调查表面粗度和磁盘的残余应力的独立影响.
评估这些表面特性对骨质细胞粘附,性酸酶 (ALP) 水平和细菌殖民的影响.

主要方法:

圆盘的表面条件有四种:光滑,光滑与残余应力,粗没有应力,和粗与残余应力.
表面特征包括光学干扰度 (粗度),接触角度测量 (湿度,表面能量) 和X射线衍射 (残余应力).
生物评估包括Saos-2骨质细胞培养 (粘附,ALP) 和细菌培养 (Streptococcus sanguinis,Lactobacillus salivarius粘附).

主要成果:

其余应力增加了表面的水友性和表面能量,特别是极性成分.
与没有残余应力表面相比,残余应力表面表现出较高的骨质母细胞粘附和ALP水平.
表面粗度是影响骨质细胞反应的主要因素.
粗的表面促进了比光滑的表面更大的细菌粘附,无论剩余应力如何.

结论:

表面的压缩余应力对骨质细胞的行为和骨质整合潜力产生积极影响.
表面粗性仍然是骨质母细胞反应和牙科植入物上的细菌殖民的一个关键因素.
结合的表面修改可以提供增强的植入物性能,需要进一步的研究.

关键词:

牙植入物是指牙植入物.砂爆炸砂爆炸砂爆炸骨质母细胞 (osteoblasts) 是一个骨质细胞.剩余压力是一种残留压力.的是什么的是什么

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