约克郡猪的生长特征的基因组预测不同的参考组大小使用不同的估计育种价值模型
Chang Yin1, Haoran Shi1, Peng Zhou1
1Department of Animal Genetics and Breeding, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Animals : an open access journal from MDPI
|April 13, 2024
概括
结合不同大小的约克郡猪种群,可显著提高基因组估计育种价值 (GEBV) 的准确性,例如生长和瘦肉百分比等特征. 这种方法提供了一种新的策略,可以在较小的群体中增强基因组选择.
科学领域:
- 动物遗传学和动物繁殖
- 量化遗传学 量化遗传学
- 牲畜中的基因组选择
背景情况:
- 中小型养猪业面临的挑战是,养殖计划所需的基准种群数据不足.
- 准确的基因组估计育种值 (GEBV) 对于改善生长和瘦肉百分比等特征至关重要.
- 基因组选择 (GS) 的准确性在具有小参考数据集的种群中可能是有限的.
研究的目的:
- 调查结合不同大小的参考种群对约克郡猪GEBV准确性的影响.
- 评估不同种群组合策略对基因组预测 (GP) 的有效性.
- 确定最佳方法来提高约克郡猪的GS准确性,特别是对于资源有限的操作.
主要方法:
- 使用GeneSeek 50K GGP猪阵列对2295只来自丹麦 (小),加拿大 (中等) 和美国 (大) 品种的约克郡猪进行基因定型.
- 使用五种GEBV模型 (BayesA,BayesB,BayesC,GBLUP,ssGBLUP) 对100公斤年龄 (AGE100) 和背部脂肪厚度 (BF100) 的基因组预测准确度的评估.
- 三种种群组合场景的比较:所有种群组合,两个种群预测第三种,以及独立的预测.
主要成果:
- 使用同一品种的其他两种种群的数据预测目标种群产生了最高的GS准确性.
- 结合不同的约克郡猪种群有效地改善了GEBV的生长和瘦肉特征.
- 这一策略特别有利于在中小型群体中增强GEBV.
结论:
- 结合不同大小的参考种群是一种可行的策略,可以提高约克郡猪的基因组选择精度.
- 这种方法为改善育种价值预测提供了一种新的方法,特别是对于数据资源有限的农民来说.
- 这些发现强调了在遗传模型中战略性种群组合对于有效养猪的重要性.
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