作为ASIC1a抑制剂的新型化学型,4-醇) - - 胺

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Updated: Jun 28, 2025

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine

Published on: June 13, 2022

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Maksym Platonov1,2, Oleksandr Maximyuk3, Alexey Rayevsky1,2,4

  • 1Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Zabolotnogo Str., 150, 03143 Kyiv, Ukraine.

International journal of molecular sciences
|April 13, 2024
PubMed
概括

酸感应离子通道 (ASIC) 对神经元功能和疾病至关重要. 这项研究揭示了阿米洛里德抑制ASIC1a的结构基础,为神经系统疾病确定了新的潜在治疗方法.

关键词:
对酸敏感的离子通道自动补丁的自动化补丁发现药物的发现.选试验 选试验 选试验虚拟选 虚拟选 虚拟选

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