循环度与脂质积累产物有积极的关系:基于人口的横截面研究
Kunsheng Zhao1, Yun Zhang1, Wenhai Sui1
1National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences; Department of Cardiology, Qilu Hospital of Shandong University, Jinan 250012, China.
Nutrients
|April 13, 2024
概括
循环 (CSe) 度与脂质积累产物 (LAP) 有正相关,这是代谢综合征的标志物. 这种非线性关联在超过12,000名成年人中观察到,根据性别和吸烟状况而有所不同.
科学领域:
- 生物化学 生化学
- 代谢健康 代谢健康
- 营养科学 营养科学
背景情况:
- 脂质积累产物 (LAP) 是代谢综合征和肥胖的一个关键指标.
- 循环 (CSe) 水平与LAP之间的关系尚未得到充分证实.
研究的目的:
- 调查成年人循环度和脂质积累产品之间的相关性.
- 探索影响这种关联的潜在改变因素.
主要方法:
- 一项涉及12815名年龄在20岁及以上的成年人的横截面研究.
- 以混变量进行调整的统计分析.
- 亚组分析检查年龄,性别,吸烟和中风的相互作用影响.
主要成果:
- 在CSe和LAP之间发现了显著的正相关性 (β = 0.41,p < 0.001).
- 较高的CSe四分位数与LAP的增加有关.
- 观察到一个积极的非线性趋势,男性和目前的吸烟者之间存在更强的关联.
结论:
- 在成年人中,循环与LAP正面且非线性相关.
- 性和吸烟状态显著改变了这种关系.
- 需要进一步的研究来阐明潜在的机制.
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