相关实验视频

Updated: Jun 28, 2025

Measuring Lactase Enzymatic Activity in the Teaching Lab

Measuring Lactase Enzymatic Activity in the Teaching Lab

Published on: August 6, 2018

益生菌策略来管理乳糖不耐症症状

Gloria Angima¹, Yunyao Qu^1,2, Si Hong Park¹

¹Department of Food Science & Technology, Oregon State University, Corvallis, OR 97331, USA.

|April 13, 2024

概括

乳糖不耐受性影响了世界上大多数人,因为乳糖不持久性. 益生菌策略,如银河类糖 (GOSs),可以通过改变肠道微生物组来帮助管理症状.

科学领域:

人类生理学和遗传学人类生理学和遗传学
微生物组研究的研究.
营养科学营养科学

背景情况:

乳糖不耐症,影响全球65-75%,源于乳糖酶的遗传缺陷,乳糖是消化乳糖 (乳糖) 的酶.
症状包括腹痛,胀气和腹,影响世界人口的很大一部分.
乳糖持续性是一种使乳糖在断奶后消化成为可能的遗传变异,被认为是对乳制品消费的进化适应.

研究的目的:

审查乳糖不耐症 (乳糖酶不持续性) 的原因.
评估益生菌干预措施对治疗乳糖不耐症症状的有效性.
探讨银河和低剂量乳糖在减轻症状中的作用.

主要方法:

对乳糖不耐症病因学研究的文献综述.
对益生菌策略的研究分析,特别是GOS和低剂量乳糖的研究.
检查这些干预措施对肠道微生物组的组成和功能的影响.

主要成果:

乳糖不耐症主要是一种遗传性疾病 (乳糖不持久性),仅通过饮食无法改变.
益生菌策略,包括GOS和低剂量乳糖,显示出改变肠道微生物群的潜力.
这些微生物组的变化可能会减轻常见的乳糖不耐症症状.

结论:

虽然不能改变乳糖不耐症的遗传基础,但症状可能可以被管理.
益生菌方法,特别是GOS和控制的低剂量乳糖摄入,为缓解症状提供了一个有希望的途径.
对微生物组调节的进一步研究是有效的乳糖不耐症管理的必要条件.

关键词:

这种细菌是Bifidobacterium.这是一种β-galactosidase.银河系酸和酸是酸的组成部分.催产卵脱落症是什么意思?乳糖酶-化氨酸酸酶.

更多相关视频

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods

Published on: September 10, 2016

Analysis of Fucosylated Human Milk Trisaccharides in Biotechnological Context Using Genetically Encoded Biosensors

Analysis of Fucosylated Human Milk Trisaccharides in Biotechnological Context Using Genetically Encoded Biosensors

Published on: April 13, 2019

相关概念视频

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...

Drugs for Treatment of Constipation-Predominant IBS

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...

Irritable Bowel Syndrome III: Medical and Nursing Management

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.

Drugs for Treatment of Diarrhea-Predominant IBS

Drugs for Treatment of Diarrhea-Predominant IBS

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are...

Hydrolysis

Hydrolysis

Overview
Hydrolysis is a chemical reaction in which the addition of water breaks down a polymer into its simpler monomer units. For example, peptides break into amino acids, carbohydrates into simple sugars, and DNA into nucleotides. Enzymes often facilitate these processes.
Hydrolysis Reverses Dehydration Synthesis
Complex carbohydrates can be broken down by breaking the bonds between individual sugar units. The reaction breaks a glycosidic bond as water is added to the compound. The...