运动对成人肠道微生物群的影响:系统性审查和元分析
Leizi Min1, Alimjan Ablitip1, Rui Wang1
1Division of Sports Science and Physical Education, Tsinghua University, Beijing 100084, China.
Nutrients
|April 13, 2024
概括
定期运动显著提高了成年人肠道微生物群的多样性,特别是增加了香农指数. 这种干预也会改变细菌的组成,在女性和老年人中观察到显著的变化.
科学领域:
- 微生物组研究的研究.
- 运动生理学 运动生理学
- 人类健康 人类健康 人类健康
背景情况:
- 肠道微生物群 (GM) 的平衡对宿主健康和代谢功能至关重要.
- 众所周知,运动会影响肠道细菌,但它对转基因多样性的影响需要综合.
研究的目的:
- 量化评估运动对成年肠道微生物群多样性的影响.
- 利用系统审查和元分析进行全面评估.
主要方法:
- 在多个数据库 (PubMed,Ebsco,Embase,Web of Science等) 进行了搜索. 在2023年9月之前.
- 包括25项研究与1044名参与者使用16S rRNA基因测序.
- 分析了与对照组比较转基因组合的运动干预研究.
主要成果:
- 运动显著增加了成年GMα多样性 (香农指数:WMD=0.05,p=0.05).
- 运动改变了转基因成分,减少了Bacteroidetes和增加了Firmicutes (改变了Firmicutes/Bacteroidetes的比率).
- 女性和老年人表现出更显著的多样性变化 (香农指数,观察到的OTU).
结论:
- 运动是改善成人肠道微生物群的有希望的策略.
- 运动后的香农指数显著增加突出了改善的多样性.
- 年龄和性别影响了转基因对运动的反应,需要进一步调查.
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