在SIBO的管理中,草药补充剂和益生菌是否补充抗生素和饮食? 一个随机临床试验
Lucia Redondo-Cuevas1, Lucia Belloch1, Vanesa Martín-Carbonell1,2
1Valencian Digestive Institute (IVADI), 46021 Valencia, Spain.
这项关于小肠细菌过度生长 (SIBO) 的研究发现,虽然草药补充剂和益生菌没有显著减少气体,但它们改善了临床结果,特别是在甲阳性SIBO患者中.
科学领域:
- 胃肠病学 胃肠病学
- 微生物学 微生物学
- 内部医学 内部医学
背景情况:
- 小肠细菌过度生长 (SIBO) 的特点是小肠中的微生物失调,导致显著的腹部症状.
- 对SIBO有效的管理策略对于改善患者的生活质量至关重要.
研究的目的:
- 评估将草药补充剂和益生菌与标准SIBO治疗方案相结合的疗效.
- 为了比较标准护理和强化治疗方案之间的治疗结果,包括草药和益生菌.
主要方法:
- 一组179名被诊断患有SIBO (分类为-SIBO或甲-SIBO) 的患者被纳入.
- 干预组接受了标准的抗生素治疗,低FODMAP饮食,以及草药抗生素,益生菌和益生菌.
- 对照组接受了标准的抗生素治疗和低FODMAP饮食.
主要成果:
- 两组治疗后的气体水平都降低了,甲-SIBO (CH4-SIBO) 患者的改善更大.
- 干预组的临床缓解率更高,特别是在CH4-SIBO病例中.
- 通过后勤回归,初始气体度被确定为治疗成功的重要预测指标.
结论:
- 辅助草药补充剂和益生菌并没有显著改变SIBO患者的气体水平.
- 然而,这些补充显示出增强临床改善的潜力,特别是在甲占主导地位的SIBO.中.
- 进一步的研究可能会阐明这些辅助疗法在SIBO管理中的具体机制和最佳使用.
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