在健康人群中,急性同度和动态运动不会改变大脑交感神经活动
Michael M Tymko1,2, Audrey Drapeau3,4, Maria Augusta Vieira-Coelho5,6
1Integrative Cerebrovascular and Environmental Physiology SB Laboratory, Department of Human Health and Nutritional Sciences, College of Biological Science, University of Guelph, Guelph, Canada.
大脑交感神经活动 (SNA) 在健康个体的运动或运动后闭塞期间不会发生变化. 这表明,大脑SNA对于运动诱导的大脑血管适应并非必不可少.
科学领域:
- 身体生理学 身体生理学
- 神经科学是一个神经科学.
- 心血管研究研究心血管研究
背景情况:
- 在运动等生理性压力期间,大脑交感神经活动 (SNA) 的作用尚未完全理解.
- 诺拉丁上腺素 (NA) 溢出是评估交感神经系统活动的验证标志物.
研究的目的:
- 为了研究等比手握运动,运动后的循环阻塞和动态自行车运动对大脑上腺素 (NA) 溢出的影响.
- 为了确定大脑SNA在急性运动和随后的恢复期间是否被激活.
主要方法:
- 12名健康参与者同时接受了动脉和内静脉血液采样.
- 使用多普勒超声波测量大脑血流量,并注入三化NA以量化溢出.
- 持续监测包括心率和血压在内的生理参数.
主要成果:
- 与休息相比,总的NA溢出在握手运动,运动后闭塞和骑自行车期间显著增加.
- 然而,大脑NA溢出在所有测试条件 (休息,运动和闭塞) 中保持不变.
- 这些发现表明,系统性和大脑对运动的同情反应之间存在分离.
结论:
- 在急性运动期间血压的暂时升高不会激活大脑SNA在健康的人.
- 大脑SNA可能不是在体力炼期间调节大脑血流的强制性组成部分.
- 这些结果挑战了关于大脑SNA对于运动相关的脑血管调整的必要性的现有观念.
更多相关视频
06:30Quantifying Acute Changes in Renal Sympathetic Nerve Activity in Response to Central Nervous System Manipulations in Anesthetized Rats
Published on: September 11, 2018
09:04Skeletal Muscle Neurovascular Coupling, Oxidative Capacity, and Microvascular Function with 'One Stop Shop' Near-infrared Spectroscopy
Published on: February 20, 2018
相关概念视频
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Sympathetic Activation
Regulation of Heart Rates
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Disorders of the Autonomic Nervous System
Raynaud's disease, also known as Raynaud's...
Autonomic Nervous System
The ANS comprises two main divisions: the sympathetic and parasympathetic divisions. These divisions function antagonistically to maintain a dynamic...
The Parasympathetic Nervous System
