免疫营养对接受结肠直肠癌手术的患者营养状况的影响:一项随机对照临床试验
Bedriye Ural1, Elvan Yılmaz-Akyüz1, Cebrail Akyüz2
1Department of Nutrition and Dietetics, University of Health Sciences, Istanbul, Turkey.
术后免疫营养 (IMN) 在结直肠癌患者中改善了人体测量和生化标志物,比单独的术前IMN更多. 这种营养策略有助于恢复,而不会影响住院或并发症.
科学领域:
- 临床营养学 临床营养学
- 手术瘤学手术瘤学
- 胃肠病学 胃肠病学
背景情况:
- 结肠直肠癌手术往往导致营养缺乏和增加并发症风险.
- 免疫营养 (IMN) 在手术患者中显示出潜在的益处.
- 在结直肠癌中IMN (术前与术后) 的最佳时间仍在研究中.
研究的目的:
- 为了比较术前免疫营养 (IMN) 与术前免疫营养对结直肠癌患者营养和生化参数的影响.
- 评估不同IMN时间对人体测量,住院和术后并发症的影响.
主要方法:
- 一项涉及50名结直肠癌患者的研究分为两组.
- 第1组接受了手术前的IMN和标准的术后营养.
- 第二组接受了手术前和手术后的IMN (口服补充阿金,omega-3脂肪酸和核酸).
主要成果:
- 与手术前单独使用IMN (组1) 相比,术后IMN (2组) 的身体重量,BMI和MUAC的保存显著更好.
- 第二组在术后表现出改善的生化标志物 (较低的CRP,AST,FPG;较高的白蛋白).
- 两组之间在住院时间或术后并发症率方面没有发现显著差异.
结论:
- 术后免疫营养比术前IMN更有效,可以改善结直肠癌患者的人类测量和生化状态.
- 这种增强的营养方法支持更好的恢复指标,而不会增加逗留时间或并发症.
- 术后的IMN代表了优化结直肠癌手术后患者结果的有价值策略.
更多相关视频
13:37A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
Published on: March 12, 2014
06:46Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
Published on: September 27, 2024
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Enteral Nutrition I: Orogastric and Nasogastric Feeding
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Tumor Immunotherapy
