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Updated: Jun 28, 2025

Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis
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Identifying Transcription Factor Olig2 Genomic Binding Sites in Acutely Purified PDGFRα+ Cells by Low-cell Chromatin Immunoprecipitation Sequencing Analysis

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转录因子Olig2是基脱甲基酶Phf8在基质细胞发育过程中的主要下游效应因子

Marco Kremp1, Tim Aberle1, Elisabeth Sock1

  • 1Institut für Biochemie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.

Glia
|April 13, 2024
PubMed
概括

Phf8蛋白质,一种基因组脱甲基酶,通过影响寡类细胞前代细胞,影响神经发育. Phf8促进了它们的增殖,但阻碍了分化,影响了中枢神经系统的发育.

关键词:
赛德里乌斯哈梅尔综合征是什么意思在这种情况下,染色染色素基因组脱甲基酶 (Histone Demethylase) 是一种基因组脱甲基酶.骨髓蛋白是什么意思 骨髓蛋白是什么意思一个小分子基细胞.

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