心血管磁共振的参考范围从健康的心脏联盟开始
Zahra Raisi-Estabragh1, Liliana Szabo2, Celeste McCracken3
1William Harvey Research Institute, NIHR Barts Biomedical Research Centre, Queen Mary University of London, Charterhouse Square, London, United Kingdom; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, West Smithfield, London, United Kingdom.
JACC. Cardiovascular imaging
|April 13, 2024
概括
这项研究建立了关键的年龄,性别和种族特异性心血管磁共振 (CMR) 参考范围,从一个大型,多样化的队列. 这些发现为准确的临床解释心脏结构和功能提供了必要的基准.
科学领域:
- 心脏病学 心脏病学
- 医疗成像医学成像
- 生物统计学 生物统计学
背景情况:
- 缺少心血管磁共振 (CMR) 的人口分层参考范围,阻碍了准确的临床解释.
- 现有的CMR数据往往缺乏年龄,性别和种族的多样性.
研究的目的:
- 为从心血管磁共振 (CMR) 获得的心房和心室指标建立全面的,人口分层的参考范围.
- 从一个大型,多元化的国际队列中提供特定于年龄,性别和种族的CMR参考值.
主要方法:
- 来自健康心脏联盟的9088项心血管磁共振 (CMR) 研究的分析.
- 使用经过认证的软件 (cvi42) 和专家阅读器进行图像分析.
- 采用了三种细分方法 (光滑,乳头,解剖) 来得出心室和心房度量,按年龄,性别和种族分层.
主要成果:
- 包括9,088名18-83岁的健康个体 (49%男性,51%女性).
- 民族多样性很高:81.7%是白人,5.6%是南亚人,5.3%是混血/其他,3.7%是黑人,3.7%是中国人.
- 使用主要供应商 (1.5-T和3.0-T扫描仪) 获取的数据 (西门子,飞利浦,通用电气).
结论:
- 这项工作提供了健康的心血管磁共振 (CMR) 衍生体积参考范围的宝贵资源.
- 已建立的范围已经准备好用于临床实施,以提高诊断准确度.
- 便于在不同人群中对CMR研究进行标准化解释.
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