在典型的煤炭火源中的多环芳香化合物的迁移模式和健康风险评估
Dandan Xu1,2, Handong Liang3,4, Peng Gao2
1State Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources, Beijing, 100083, China.
Environmental science and pollution research international
|April 13, 2024
概括
伍达煤火释放出高水平的多环芳香化合物 (PAC),包括多环芳香 (PAH),进入周围的土壤. 这些污染物带来了显著的癌症风险,需要进一步研究它们的环境迁移.
科学领域:
- 环境化学环境化学
- 有机地化学 有机地化学
- 污染研究 污染研究
背景情况:
- 乌达煤火是全球有机污染物的主要来源,特别是多环芳香化合物 (PAC).
- 由于其毒性和持久性,PACs是一个重大的环境问题.
- 有限的系统研究存在于煤炭火灾中PACs的丰富和迁移模式.
研究的目的:
- 调查从武达煤火中排放的PACs的缩和迁移模式.
- 为了比较煤炭火灾海绵样本和周围土壤中的PAC水平.
- 评估与这些污染物相关的癌症风险,并探索形成机制.
主要方法:
- 使用气体染色学-气体染色学-飞行质谱时间 (GC×GC-TOFMS) 分析了47个PAC.
- 在煤火海绵和土壤样本中比较PAC度.
- 癌症风险评估和氧化PAH形成的调查.
主要成果:
- 煤火海绵样本显示,与周围土壤相比,16种多环芳 (16PAHs) (15400.65 ng/g) 的度显著更高 (4.2倍低).
- 检测到31种PAC的含量明显超过了16种PAH的含量.
- 煤火源主要产生和储存16PAHs,而土壤积累PAH衍生物,包括氧化PAHs在迁移过程中氧化形成.
结论:
- 煤炭火灾是有毒PACs的重要来源,在火灾现场和周围环境中都存在相当大的癌症风险.
- 氧化PAHs是通过16PAHs和化PAHs在迁移到土壤期间的氧化而形成的.
- 甲与基化甲 (<2) 的比率可以作为煤炭火灾污染的特征标记.
更多相关视频
11:38High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
12.2K
09:50Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
11.2K
相关概念视频
Cancer Prevention
6.2K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
6.2K
Statistical Methods for Analyzing Epidemiological Data
364
Epidemiological data primarily involves information on specific populations' occurrence, distribution, and determinants of health and diseases. This data is crucial for understanding disease patterns and impacts, aiding public health decision-making and disease prevention strategies. The analysis of epidemiological data employs various statistical methods to interpret health-related data effectively. Here are some commonly used methods:
364
Mutagenicity and Carcinogenicity
1.3K
Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...
1.3K
Types of Toxins
1.7K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
1.7K
Observational Studies
8.5K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
8.5K
Gas Chromatography: Types of Detectors-II
368
In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
368
