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Updated: Jun 28, 2025

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
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Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag

Published on: December 14, 2017

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自体主导帕金森病中的RAB32 Ser71Arg:联系,关联和功能分析

Emil K Gustavsson1, Jordan Follett2, Joanne Trinh3

  • 1Department of Genetics and Genomic Medicine, Great Ormond Street Institute of Child Health, University College London, London, UK; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; Aligning Science Across Parkinson's Collaborative Research Network, Chevy Chase, MD, USA.

The Lancet. Neurology
|April 13, 2024
PubMed
概括

一种新的RAB32基因变异 (Ser71Arg) 与帕金森病有关,影响多个种族. 这一发现突出了家族性帕金森症的共享机制,并表明细胞内免疫在疾病遗传起源中的作用.

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