两个罕见的良性卵巢瘤病例与恶性复发
Kanella Kantreva1, Stavroula A Paschou1, Katerina Stefanaki1
1Endocrine Unit and Diabetes Center, Department of Clinical Therapeutics, Alexandra Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Endocrinology, diabetes & metabolism case reports
|April 13, 2024
概括
卵巢瘤恶性转化为高度分化的卵巢卵泡癌是罕见的. 这份报告详细介绍了两个卵巢瘤的病例,最初是良性的,后来显示恶性转变和转移.
科学领域:
- 妇科瘤学 妇科瘤学
- 内分泌学 在内分泌学.
- 病理学 病理学 病理学
背景情况:
- 卵巢瘤,一个卵巢瘤,占所有卵巢瘤的2-5%.
- 卵巢的恶性转变非常罕见,发生在不到5%的病例中,转移性疾病更为罕见.
研究的目的:
- 报告两例良性卵巢瘤的病例,这些病例经历了恶性转变为卵巢高度差异化的卵泡癌 (HDFCO).
- 突出诊断HDFCO的挑战,并讨论恶性卵巢瘤 (MSO) 的治疗方法.
主要方法:
- 在初始良性卵巢瘤诊断后诊断出HDFCO的两名患者的病例报告分析.
- 对临床和组织学特征,包括手术,全甲状腺切除和放射性 (131I) 治疗在内的治疗方法的审查.
主要成果:
- 案例1:一名37岁的女性患有HDFCO和多种转移,此前在14年前被诊断患有良性卵巢瘤.
- 案例2:一名26岁的女性患有HDFCO,在6年前初始良性卵巢瘤诊断后4年经历了复发.
- 两位患者都接受了手术治疗,全甲状腺切除术和放射性治疗.
结论:
- 卵巢的恶性转变,虽然很少见,但需要仔细评估和管理.
- 对MSO的术后治疗决策应以临床和组织学评估为指导.
- 对于MSO患者来说,长期随访涉及TSH抑制和铁球蛋白水平监测至关重要.
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