对诊断动脉炎的成本效益分析
Isabel Del Blanco Alonso1, Álvaro Revilla Calavia1, Laura Saiz-Viloria1
1Servicio de Angiología y Cirugía Vascular, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
Reumatologia clinica
|April 13, 2024
概括
使用临床标准结合多普勒超声波或活检诊断关动脉炎 (TA),以及暂停皮质类固醇,大大降低了成本. 这些策略为诊断这种常见的血管炎提供了相当大的节约.
科学领域:
- 类风湿病学 类风湿病学
- 系统性血管炎 系统性血管炎
- 卫生经济学 卫生经济学
背景情况:
- 时间性动脉炎 (TA) 是系统性血管炎的最常见形式.
- 目前的诊断依赖于美国风湿病学学院的标准,标准治疗是高剂量的皮质类固醇.
- 需要评估TA诊断和治疗策略的经济影响.
研究的目的:
- 评估时间性动脉炎 (TA) 的诊断成本.
- 对TA的各种诊断 (临床,活检,多普勒超声波) 和治疗 (皮质类固醇悬浮) 策略进行成本效益分析.
主要方法:
- 在2012年至2021年期间被诊断为TA的患者进行了一项观察性回顾性研究.
- 收集的数据包括人口统计,并发症和暗示TA的症状.
- 使用美国风湿病学学院评分 (ACR-SCORE) ≥3来确认诊断;分析了诊断和治疗修改的成本.
主要成果:
- 头痛,部疼痛和关节障碍是TA诊断的重要指标.
- 患有多普勒超声波光环或阳性活检的患者显示ESR和CRP升高.
- 诊断成本为414.7欧元/患者;ACR-SCORE ≥3与多普勒超声波 (167.2欧元/患者) 和活检 (339.75欧元/患者) 显示显著节省 (分别为59.6%和18%).
结论:
- 临床症状,如头痛,部疼痛和关节障碍是TA的关键预测因素.
- 升高的ESR和CRP预测了活检结果和超声波光的阳性.
- 使用ACR-SCORE ≥3与多普勒超声波或活检,以及皮质类固醇悬浮剂,为TA管理提供了一种具有成本效益的方法.
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