相关实验视频

Updated: Jun 28, 2025

Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation
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Fabrication of Anisotropic Polymeric Artificial Antigen Presenting Cells for CD8+ T Cell Activation

Published on: October 12, 2018

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表面功能化的微凝作为人工抗原呈现细胞,以调节T细胞的扩张

Junzhe Lou1,2, Charlotte Meyer1,3, Einat B Vitner1

  • 1Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, 02138, USA.

Advanced materials (Deerfield Beach, Fla.)
|April 14, 2024
PubMed
概括

研究人员开发了可调节的微凝,作为人工抗原呈现细胞 (aAPC),有效扩展和控制T细胞用于癌症治疗. 这种模块化系统提供了T细胞激活和表型的精确调节.

关键词:
在T细胞激活过程中,抗原特异性T细胞扩张.有颗粒状的水凝.微凝是一种微凝.表面功能化的功能化.粘性弹性 粘性弹性

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T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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