慢性患者在1.4 ATA的高压治疗期间的皮肤透氧氧度值与2 ATA相比为1.4 ATA
Ram A Sack1,2, Yoav Yechezkel Pikkel3, Ortal Leitner Shemy3
1Rambam Hyperbaric Pressure Chamber, Rambam Health Care Campus, Haifa, Israel.
概括
低压高压室,通常用于家庭使用,提供氧气在压力不足治疗慢性伤口. 临床试验显示,与标准高压氧气疗法 (HBOT) 相比,氧气水平显著降低.
科学领域:
- 高压医学的高压医学.
- 伤口护理 伤口护理
- 氧气疗法是一种氧气疗法.
背景情况:
- 慢性伤口严重损害患者的生活质量,因为氧气供应不足.
- 高压氧气疗法 (HBOT) 是一种成熟的治疗方法,但正在出现向低压室的趋势.
- 低压 (1.3 ATA) 室,通常用于家庭使用,被推广为相当于临床HBOT,但使用较低的氧气压力.
研究的目的:
- 为了评估1.4 ATA高压治疗慢性的疗效.
- 为了比较通过1.4 ATA与标准的2 ATA HBOT实现的透皮氧气压 (TcPO2) 水平.
主要方法:
- 130名患有慢性的患者参与了这项研究.
- 透皮氧气压 (TcPO2) 测量在附近,同时呼吸100%氧气在1.4 ATA5分钟和10分钟.
- 结果与2 ATA.历史数据进行了比较.
主要成果:
- 10分钟后1.4 ATA的平均TcPO2为161 mmHg,明显低于2 ATA的333 mmHg (p < 0.001).
- 所有的电极测试都显示了1.4 ATA和2 ATA之间的统计学上显著差异.
- 没有证据支持1.4 ATA治疗对慢性患者有益的说法.
结论:
- 目前的证据不支持使用1.4 ATA高压治疗慢性的使用.
- 低压高压治疗的有效性需要严格的科学研究和基于证据的数据.
- 需要进一步的研究来确定1.4 ATA对各种疾病的实际影响.
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