静止体积与呼吸暂停引起的血红蛋白质量增加之间的关系
Jason M Keeler1, Hayden W Hess1, Erica Tourula1
1H.H. Morris Human Performance Laboratories, Department of Kinesiology, School of Public Health, Indiana University, Bloomington, IN, USA.
概括
脏尺寸较大并不增强血红蛋白质量在健康成年人的呼吸暂停期间增加. 这项研究没有发现脏体积和呼吸炼后改善的氧气承载能力之间的联系.
科学领域:
- 生理学 生理学 生理学
- 人类的适应能力
- 潜水科学 潜水科学
背景情况:
- 具有特殊的呼吸暂停潜水技能的土著人口表现出更大的脏体积.
- 假设更大的脏可以通过脏收缩在呼吸暂停期间增加循环血红蛋白质量 (Hb质量),从而可能增强氧气 (O2) 和二氧化碳 (CO2) /pH缓冲能力.
研究的目的:
- 在健康的成年人中,研究静止体积和呼吸暂停引起的总Hb质量增加之间的关系.
- 测试假设,更大的静止体积与更大的呼吸暂停诱导的Hb质量的升高正相关.
主要方法:
- 14名健康成年人接受一氧化碳再呼吸程序,以确定呼吸暂停前的Hb质量和血液体积.
- 超声波测量评估了最大呼吸前和最大呼吸后的脏尺寸,用Pilström方程计算脏体积.
- 从毛细血管血液样本中测量了血红蛋白度和血红素值,并估计了呼吸暂停后的Hb质量.
主要成果:
- 呼吸暂停后脏体积显著减少 (247 ± 95毫升至200 ± 82毫升).
- 血红蛋白度,血红素和总Hb质量显示在呼吸暂停后显著增加.
- 静止体积与呼吸暂停后Hb质量增加的大小没有显著相关 (r = -0.02,p = 0.47).
- 氧气和CO2承载能力在呼吸暂停后增加.
结论:
- 在未接受呼吸暂停训练的健康成年人中,更大的静止体积与呼吸暂停期间Hb质量的更大增加无关.
- 在急性呼吸暂停期间,脏在增加Hb质量方面的作用可能与该人群中的休息体积不成正比.
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