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揭示内微生物群:对于结直肠癌诊断和治疗的新兴力量

Jinjing Zhang¹, Penghui Wang¹, Jiafeng Wang²

¹Affiliated Cixi Hospital, Wenzhou Medical University, Zhejiang, China.

Pharmacological research

|April 14, 2024

概括

人体含有微生物,这些微生物对健康和疾病有重大影响. 本综述探讨了内微生物群在结直肠癌 (CRC) 进展中的作用及其临床应用.

科学领域:

微生物学微生物学
在瘤学瘤学.
胃肠病学胃肠病学

背景情况:

微生物居住在人体器官中,影响生理和病理过程.
测序技术揭示了结直肠癌 (CRC) 中的内微生物群组成,这意味着它与疾病的进展有关.
发现的关键品种包括Fusobacterium,Bifidobacteria和Bacteroides.

研究的目的:

总结当前关于CRC内微生物群的知识.
概述CRC诊断,预防和治疗中的潜在临床应用.
审查微生物疗法,以提高CRC治疗的有效性和安全性.

主要方法:

文献综述和关于内微生物群和CRC的当前研究的综合.
专注于翻译和临床应用,包括诊断生物标志物和治疗策略.
对临床实施的挑战和解决方案的分析.

主要成果:

内微生物群在结直肠癌的进展中起着重要作用.
微生物疗法有望改善CRC的化疗和免疫疗法的疗效.
内微生物群有可能成为CRC诊断和预后生物标志物的来源.

结论:

了解内微生物群对于推进CRC诊断,预防和治疗至关重要.
向瘤内微生物群为结直肠癌提供了新的治疗途径.
克服转化障碍是将微生物群研究纳入临床实践的关键.

关键词:

癌症治疗治疗癌症治疗胃肠道癌症是什么意思我们的肠道微生物群.免疫治疗是一种免疫疗法.微生物生物标志物微生物生物标志物瘤的微生物群.

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