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Updated: Jun 28, 2025

Intestinal Epithelial Regeneration in Response to Ionizing Irradiation
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胃肠急性辐射综合征:机制,模型,标记物和医疗对策
Thomas A Winters1, Libero Marzella2, Olivia Molinar-Inglis1
1Radiation and Nuclear Countermeasures Program (RNCP), Division of Allergy, Immunology and Transplantation (DAIT), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Rockville, Maryland.
高剂量辐射暴露可能导致急性辐射综合征 (ARS),影响胃肠道 (GI). 研究正在推进GI-ARS的医疗对策 (MCMs),以改善患者的治疗结果.
科学领域:
- 辐射生物学 辐射生物学
- 胃肠病学 胃肠病学
- 医疗对策 医疗对策
背景情况:
- 事故或袭击造成的高剂量辐射暴露可能导致急性辐射综合征 (ARS),严重影响胃肠道 (GI).
- 胃肠道损伤导致吸收不良,脱水,电解质不平衡和障碍功能受损,增加败血症风险和死亡率.
- 辐射诱导的GI-ARS是一个关键的未满足的医疗需求,需要专门的研究和开发.
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