高血压分级的预后影响 高血压分级的预后影响
Fabio Angeli1, Paolo Verdecchia2, Gianpaolo Reboldi3
1Department of Medicine and Technological Innovation (DiMIT), University of Insubria, Varese, and Department of Medicine and Cardiopulmonary Rehabilitation, Maugeri Care and Research Institute, IRCCS Tradate, Italy.
European journal of internal medicine
|April 15, 2024
概括
高血压分级显示,1级和2级的心血管事件风险相似. 然而,严重的3级高血压 (临床血压≥180/110 mmHg) 表示更高的风险,特别是当通过24小时的门诊血压监测证实时.
科学领域:
- 心脏病学 心脏病学
- 高血压研究 高血压研究
- 临床流行病学临床流行病学
背景情况:
- 高血压指南使用定义的切断值对血压 (BP) 严重程度进行分类.
- 调查不同级别的高血压的预后意义对于风险分层至关重要.
研究的目的:
- 评估1级,2级和3级高血压对主要心血管事件的预后影响.
- 为了比较与不同高血压严重程度相关的心血管风险.
主要方法:
- 在3150名未经治疗的高血压患者中进行了为期10年的随访,这些患者之前没有患有心血管疾病.
- 使用24小时的门诊血压 (BP) 监测以及临床BP测量.
- 评估了主要的不良心血管事件,包括心肌梗塞,中风,心血管死亡和心力衰竭住院治疗.
主要成果:
- 在1级和2级高血压之间,心血管事件发生率没有显著差异.
- 3级高血压的发病率较高 (1.93每100个患者年).
- 在对共变量进行调整后,3级风险与1级相比显著,但在调整为24小时门诊静脉血压时失去了意义.
结论:
- 1级和2级高血压在相对心血管事件危险上没有显著差异.
- 3级高血压 (临床血压≥180/110 mmHg) 与心血管风险增加有关.
- 这种在3级的风险增加与更高的24小时门诊血压水平有关.
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