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Updated: Jun 28, 2025

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在EGFR抑制后的持久性之路

Purva H Rumde1, Timothy F Burns1,2,3

  • 1Division of Hematology-Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pennsylvania.

Cancer research
|April 15, 2024
PubMed
概括

在EGFR突变肺癌中,耐药性持久细胞可在向治疗后导致复发. ASCL1通过促进表皮细胞转化为介质酶细胞的转变来推动这种持久性,从而提供了潜在的新治疗点.

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