在美国退伍军人中糖尿病病的流行病学
Kibum Kim1,2,3, Jacob Crook3,4, Chao-Chin Lu3
1Department of Pharmacy Systems, Outcomes and Policy, University of Illinois Chicago, Chicago, IL, USA.
概括
糖尿病病 (DKD) 影响超过50万美国退伍军人,超过50%的退伍军人在五年内经历疾病进展或死亡. 这凸显了迫切需要改进在这一群体中的DKD识别和管理策略.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 公共卫生 公共卫生
背景情况:
- 糖尿病病 (DKD) 在美国是一个重大的健康负担,其特点是患者数量和死亡率高.
- 尽管糖尿病是慢性病的主要原因,但在美国退伍军人人口中,DKD的流行病学仍然基本上没有特征.
研究的目的:
- 为了估计美国退伍军人的DKD进展率.
- 确定美国退伍军人人口中DKD的一般流行病学.
主要方法:
- 使用退伍军人卫生管理局 (2016-2022) 电子健康记录和行政数据库进行的回顾性观察研究.
- 基于符合病:改善全球结果 (KDIGO) 准则的实验室数据进行DKD患者鉴定.
- 分析包括五年累计发病率的高级DKD或所有原因的死亡和在不同时间点的流行率.
主要成果:
- 该队列包括685,288名退伍军人 (96%是男性,平均年龄62岁).
- 五年累计发病率的高级DKD或死亡范围从47.4%到60.9%在不同的DKD阶段.
- 2021年,594,082名患者被归类为中度或高风险,G3a和G3b阶段分别占病例的51.2%和25.3%.
结论:
- 超过一半的DKD患者在五年内经历了疾病进展或死亡.
- 显著数量的早期DKD患者可能未被诊断或未得到充分治疗.
- 研究结果表明,需要对美国退伍军人的DKD患者识别和管理协议进行修订.
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