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Updated: Jun 28, 2025

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
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在生殖线TP53驱动的乳腺癌中显著的基因组和免疫瘤进化

Nabamita Boruah1, David Hoyos2, Renyta Moses1

  • 1Department of Medicine, Division of Hematology-Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

bioRxiv : the preprint server for biology
|April 15, 2024
PubMed
概括

李弗劳梅尼综合征 (LFS) 乳腺癌表现出独特的遗传变化,包括TP53损失和高形积分. 与零星癌症不同,LFS瘤无法调高关键细胞死亡基因,影响瘤的进展.

关键词:
细菌线的细菌线是什么这就是TP53的特点.继承 继承 继承 继承 继承在p53瘤抑制剂.瘤的发展 瘤的发展瘤免疫学 瘤免疫学

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