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Updated: Jun 28, 2025

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
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Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay

Published on: December 19, 2018

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雌激素受体α绑定剂用于激素依赖的乳腺癌形式:e-QSAR和分子对接由X射线解析结构支持

Vijay H Masand1, Sami A Al-Hussain2, Abdullah Y Alzahrani3

  • 1Department of Chemistry, Vidya Bharati Mahavidyalaya, Amravati 444 602, Maharashtra, India.

ACS omega
|April 15, 2024
PubMed
概括

这项研究确定了关键的分子特征,包括特定的原子和结合模式,这些特征对于抑制雌激素受体α (ER-α)至关重要. 这些发现有助于开发针对ER-α的新乳腺癌疗法.

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